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Home » Recipes » Turkey

Creamy turkey artichoke casserole

Square headshot image of Family Food on the Table's Kathryn Doherty.
By Kathryn Doherty · Modified: Mar 10, 2025 · Published: Nov 14, 2016 · This post may contain affiliate links
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Creamy turkey artichoke casserole is an easy way to transform leftover Thanksgiving turkey into an entirely different meal!Close up of a large serving spoon resting in a white baking dish with a creamy turkey artichoke casserole topped with browned breadcrumbs.

How was your weekend, friends? What did you do?

I got lots done - laundry, food prep, errands, work, etc. - had lots of play time with the kids - playground, bike rides, board games, card games, reading and snuggles - and I even got in some relaxation, which made me a very happy lady. Well-balanced weekend all around

(You may have seen some of this in action if you follow me on Instagram. I've been having fun with the Instagram stories feature recently!)

So, anyone with me on loving the Thanksgiving leftovers almost as much - and maybe even a little more - than the official meal?

A spoon scooping up a creamy turkey artichoke casserole from a white rectangular baking dish.

I don't think I used to feel that way but in recent years, I've gotten really into the leftovers. We always eat the leftovers again for dinner on Friday night and after that, I can start to get creative, transforming the leftovers into new meals.  Using them in completely different ways. And of course, making ALL the sandwiches 🙂

So this week I'm bringing you all recipes for leftover Thanksgiving turkey. Starting today with this creamy turkey artichoke casserole, continuing on Wednesday with a 15-minute dinner and capping off the week on Friday with the ultimate leftover Thanksgiving turkey sandwich. Stay tuned for deliciousness!

Here, your leftover turkey becomes a whole new meal of easy, creamy casserole goodness. This is perfect when you still have company in town and need to feed a crowd.

A collage of photos of the assembly process for a turkey artichoke casserole with breadcrumbs on top.

Or maybe you don't have leftover turkey but wish you did? Happens to me all the time. You can make my slow cooker turkey breasts with some basic seasonings (I use salt, pepper and Italian seasoning to make leftovers for things like this).

This recipe came from my Christmas Memories cookbook, one of the many that I've picked up from used bookstores over the years. I love finding community cookbooks like this with people's favorite homemade recipes - just feels like there's so much love and history there.

It's not for sale though, so no Amazon link - sorry! But at least you still get to enjoy this reicpe!

A browned baked casserole with artichokes and leftover turkey.

Notes on making turkey artichoke casserole:

  • This is designed for leftover turkey, but you could also use chicken. And you can add leftover ham if you want to do ham and turkey. Just use a total of about 4 cups of whatever meat you choose.
  • You can make this ahead through step 4. Cover the casserole and put it in the fridge. Take it out while you preheat your oven and add the breadcrumb mixture before baking so it will get crunchy. Add 5-10 minutes to the cooking time. It will be ready when it's bubbling all around the edges.
  • You can try adding some frozen spinach (that's been thawed) or some peas to have some greens in here.
  • If not, we like to serve this over rice and have some buttered peas on the side. You could also serve it over leftover mashed potatoes if you have some and do a simple spinach salad.
  • Me, who adds salt to everything, didn't think this casserole needed it at all. It will depend on the seasoning of your leftover turkey, however, so taste and adjust to your liking.

A hand holding up a scoop of a creamy turkey casserole with artichokes. A fork resting on a plate with a creamy turkey and artichoke mixture served with rice and green peas.

Be sure to stop back by for my other leftover turkey recipes this week - or sign up for my free weekly e-newsletter and never miss a post. (You'll also get my free e-cookbook, Easy Weeknight Dinners, when you sign up.)

I'd also love to connect on social media - follow me on Facebook, Instagram, Pinterest and Twitter for more recipe goodness!

Enjoy!

XO,

Kathryn

Close up of a large serving spoon resting in a white baking dish with a creamy turkey artichoke casserole topped with browned breadcrumbs.
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4.56 from 9 votes

Creamy turkey artichoke casserole

Creamy turkey artichoke casserole is an easy way to transform leftover Thanksgiving turkey into an entirely different meal!
Prep Time15 minutes mins
Cook Time20 minutes mins
Total Time35 minutes mins
Yield: 6 servings

Ingredients

  • 4 cups leftover cooked turkey, chopped
  • 1 (15.5 oz.) can artichoke hearts, drained
  • 3 tablespoons unsalted butter
  • 3 tablespoons flour
  • ½ teaspoon nutmeg
  • 2 ½ cups low-sodium chicken broth
  • 2 cups shredded sharp cheddar cheese
  • 1 tablespoon unsalted butter, melted
  • ⅓ cup plain breadcrumbs
  • ¼ teaspoon dried thyme
  • ¼ teaspoon black pepper
  • ⅛ teaspoon paprika

Instructions

  • Preheat oven to 375.
  • Place turkey and artichokes (quartered) in bottom of a greased 2-quart casserole dish.
  • Melt butter in a small saucepan over medium heat. Add flour and nutmeg and whisk to combine. Cook for 1 minute, stirring constantly.
  • Slowly add chicken broth, whisking constantly, until well combined with no lumps. Let cook 4-5 minutes until thickened. Stir in cheddar cheese until melted and turn off heat. Pour over turkey and artichokes in casserole dish.
  • Combine melted butter with breadcrumbs and remaining seasonings. Sprinkle over top of the casserole.
  • Bake at 375 for 20-25 minutes, until bubbly.

Notes

You can use a combination of leftover ham and turkey, or use leftover cooked chicken, for this casserole if you prefer.
You can make this ahead through step 4. Cover the casserole and put it in the fridge. Take it out while you preheat your oven and add the breadcrumb mixture before baking so it will get crunchy. Add 5-10 minutes to the cooking time. It will be ready when it’s bubbling all around the edges.
You can try adding some frozen spinach (that’s been thawed) or some peas to have some greens in here.
I don’t add salt to this, but depending on the seasoning of your leftover turkey, you may want to. Taste and adjust to your liking.

Video

Nutrition

Calories: 452kcal | Carbohydrates: 11g | Protein: 47g | Fat: 25g | Saturated Fat: 14g | Trans Fat: 1g | Fiber: 4g
Tried this recipe?Leave a comment below or follow me on Instagram @familyfoodonthetable and tag me in your photo!
A collage of images of a creamy turkey artichoke casserole topped with breadcrumbs. Process shots of the assembling of a turkey artichoke casserole in a white baking dish.

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Comments

  1. Dawn @ Girl Heart Food says

    November 14, 2016 at 8:49 am

    Sounds like you had a productive and fun weekend!! The best weekends, right 😉 ? We did too....little work around the house, little relaxing...a good balance! Some people don't like leftovers, but I do! I love using what's left and repurposing it and this casserole sounds delicious! Love your suggestion of adding spinach to the mix 🙂 Happy Monday! xo

    Reply
    • Kathryn says

      November 14, 2016 at 7:17 pm

      I didn't like leftovers much when I was a kid but I LOVE them now - so fun to make new things out of other dishes or scraps! Have a wonderful week girl! XO

      Reply
  2. Mona says

    November 14, 2016 at 11:21 am

    I am soooo making this! Not sure I can wait til after Thanksgiving 🙂

    Reply
    • Kathryn says

      November 14, 2016 at 7:15 pm

      I hear ya! It's great fall/winter comfort food!

      Reply
  3. Brynn at The Domestic Dietitian says

    November 14, 2016 at 6:29 pm

    Thanksgiving leftovers are fantastic! I love them even more than the actual meal too! This looks great

    Reply
    • Kathryn says

      November 14, 2016 at 7:15 pm

      Leftovers are definitely where it's at 😉 Thanks Brynn!

      Reply
      • kate @ Framed Cooks says

        November 15, 2016 at 5:56 am

        The leftovers are the BEST, because they turn into suppers like this one! CAN'T. WAIT.

        Reply
        • Kathryn says

          November 15, 2016 at 4:24 pm

          Completely agree!! 😀

          Reply
  4. Lynn O'Brien says

    October 24, 2017 at 3:03 pm

    Needs some mushrooms and a few slices of red pepper ,and parsley

    Reply
    • Kathryn says

      October 24, 2017 at 10:28 pm

      Great ideas! I also mention spinach and peas as possible additions in the blog post. Lots of ways to customize this and add some veggies!

      Reply
  5. Lindsay @ The Live-In Kitchen says

    October 25, 2017 at 3:05 pm

    Great twist on a classic supper!

    Reply
    • Kathryn says

      October 26, 2017 at 8:31 am

      Thanks Lindsay! 😊

      Reply
  6. Carolyn Ingram says

    October 27, 2017 at 8:18 pm

    This sounds perfect!

    Reply
    • Kathryn says

      October 30, 2017 at 10:14 am

      It's delicious! I hope you try it!

      Reply
  7. Allie says

    May 20, 2020 at 7:06 am

    Think you could use Italian blend cheese instead of cheddar? Trying to avoid going to the store.

    Reply
    • Kathryn Doherty says

      May 20, 2020 at 8:24 am

      Yes, I think those flavors would work great for this! 😊 Would love to hear if you try it!

      Reply
      • Nicole Willard says

        July 14, 2024 at 9:20 pm

        I was looking for something a little different to try. I will be making this tomorrow! It sounds delicious;

        Reply
  8. Jim says

    November 29, 2020 at 6:47 pm

    Tried the recipe, and the family did like it, though I could not bring myself to add the nutmeg, which seemed wholly out of place. If I make it again, I will cut down the chicken stock to 2 cups or less, and about 1/2 cup more cheese. Adding leftover broccoli worked well.

    Reply
    • Kathryn Doherty says

      December 01, 2020 at 3:15 pm

      Glad you all enjoyed it! So happy you adapted it to suit you and love the addition of broccoli - yum!

      Reply
4.56 from 9 votes (9 ratings without comment)

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Meet Kathryn

Hi there! I’m Kathryn Doherty, a cookbook author, mom of two, and devoted food and home cooking nut. I’ve got lots of easy recipes to help you get delicious food on the table for your family!

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