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Home » Recipes » Main Dishes

Mexican Meatloaf

By: Kathryn Doherty | Last Updated: Mar 6, 2025 | Published: Jan 17, 2016
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This easy, 1-bowl Mexican meatloaf is made with ground turkey, cheese, chilies and salsa! It's perfect for a hands-off dinner the whole family will love!

A sliced meatloaf on a white platter with a salsa topping and fresh parsley to the side.


 

I may aspire to lazy Sundays of sleeping in, reading the paper and preparing a dinner that cooks all day so we can sit around the table enjoying each other's company...

Instead, we have dinner that I’m lucky to squeak out and get onto the table before I collapse in a heap at the end of the day.

And despite the chaos, I still demand healthy, fresh and flavorful.

This Mexican meatloaf seriously checks each of those boxes AND it’s super, super easy.

Baked Mexican style turkey meatloaf on a white platter with a salsa topping and fresh parsley to the side.

Put all of your ingredients into a bowl (yup, just one bowl!), mix very well, shape into a loaf and bake.

Yup, that's it!

And you'll have yourself a crowd-pleasing, cheesy, healthified (hello ground turkey and chopped fresh spinach, I’m looking at you) and flavor-packed meatloaf ready for devouring.

Here are a few quick notes and tips for the recipe.

Ingredient Notes:

  • Ground turkey: Lean ground turkey (the 93% lean kind) is my go-to for meatloaf. My package from the grocery store is usually 1.25 pounds, but I’ve also made this with a 1-pound package and that was fine, too. You could probably also substitute lean ground beef or use ground chicken if you prefer.
  • Onion: Make sure to chop it finely so you don't have big chunks of onion in your meatloaf. You could also grate it if you prefer.
  • Salsa: Use your favorite jarred salsa and whatever heat level you prefer - mild, medium or hot. I would stay away from any sort of bean-based or fruity salsa for this recipe.
  • Breadcrumbs: I use store-bought plain breadcrumbs for this recipe. You can use gluten-free breadcrumbs to make this meatloaf gluten free.
Close up of a sliced ground turkey Mexican meatloaf topped with salsa on a serving platter with fresh parsley as a garnish.

As for serving, add some brown rice or maybe some paprika potatoes (or my go-to 10-minute microwave “baked" potatoes) or go with mashed potatoes if you like.

Then you just need a vegetable - maybe some green beans, steamed broccoli or a really simple spinach salad.

Very versatile.

Suddenly, you have a complete dinner spread! Worthy even of a Sunday!

A sliced turkey meatloaf on a white platter with a salsa topping and fresh parsley to the side.

Maybe one day I'll cook all-day meals. Most likely not.

Most likely I'll stick to quick, easy and delicious meals like this one.

I hope you give this recipe a try for a fun new way to do meatloaf!

Enjoy!

XO,

Kathryn

P.S. Are you a meatloaf lover? Me too! Check out my BBQ cheddar turkey meatloaf — another 1-bowl turkey meatloaf that packs a serious flavor punch.

You can also try this classic turkey meatloaf or these mini turkey meatloaves that are individually sized.

Close up of a sliced ground turkey Mexican meatloaf topped with salsa on a serving platter with fresh parsley as a garnish.
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4.35 from 49 votes

Mexican Meatloaf

This easy, 1-bowl Mexican meatloaf is made with ground turkey, cheese, chilies and salsa! It's perfect for a hands-off dinner the whole family will love!
Prep Time10 minutes mins
Cook Time45 minutes mins
Additional TimeInactive Time5 minutes mins
Total Time1 hour hr
Yield: 4 -6 servings

Ingredients

  • 1 ¼ pounds ground turkey (see notes)
  • 1 small yellow onion, finely chopped (about 1 cup)
  • ½ cup plain breadcrumbs
  • 1 large egg, beaten
  • 1 cup shredded sharp cheddar or Monterey Jack cheese
  • ¾ cup salsa, divided
  • 1 cup packed spinach leaves, chopped
  • 1 (4 oz.) can chopped green chilies
  • 1 teaspoon chili powder
  • ¾ teaspoon kosher salt
  • ¼ teaspoon black pepper
  • extra cheese and salsa, for serving, if desired

Instructions

  • Preheat the oven to 400. Line a baking sheet with parchment paper for easy clean up if desired.
  • In a large bowl, add all of the ingredients (using just ½ cup salsa). Mix well. I start with a fork to get it going then use my hands so I don’t overwork it.
  • Turn the meatloaf mixture out onto the baking sheet and shape into a loaf, about 8 inches long.
  • Top with remaining ¼ cup salsa and bake at 400 for 45 minutes, until cooked through.
  • Remove and let stand for 5-10 minutes before slicing. Serve hot and enjoy!

Notes

Ground turkey: Lean ground turkey (the 93% lean kind) is my go-to for meatloaf. My package from the grocery store is usually 1.25 pounds, but I’ve also made this with a 1-pound package and that was fine, too. You could probably also substitute lean ground beef or use ground chicken if you prefer.
Onion: Make sure to chop it finely so you don't have big chunks of onion in your meatloaf. You could also grate it if you prefer.
Salsa: Use your favorite jarred salsa and whatever heat level you prefer - mild, medium or hot. I would stay away from any sort of bean-based or fruity salsa for this recipe.
Breadcrumbs: I use store-bought plain breadcrumbs for this recipe. You can use gluten-free breadcrumbs to make this meatloaf gluten free.

Nutrition

Serving: 1serving | Calories: 510kcal | Carbohydrates: 13g | Protein: 39g | Fat: 34g | Saturated Fat: 14g | Polyunsaturated Fat: 16g | Trans Fat: 1g | Cholesterol: 177mg | Sodium: 1033mg | Fiber: 2g | Sugar: 3g
Tried this recipe?Leave a comment below or follow me on Instagram @familyfoodonthetable and tag me in your photo!
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Reader Interactions

Comments

  1. cesar

    July 10, 2017 at 7:17 am

    Thank you for sharing your knowledge with us.

    Reply
  2. Pedro

    July 14, 2017 at 8:50 am

    I love Mexican food. Thanks for the recipe.

    Reply
  3. Adriana Silva

    July 31, 2017 at 12:16 pm

    Thanks for the recipe i´ll try it out!

    Reply
  4. Fernando

    August 09, 2017 at 7:08 pm

    Great to lunch at work 🙂

    Reply
  5. Jairo Dourado

    August 16, 2017 at 4:23 pm

    Nice one. Its look so good. I will try this recipe. Thanks for sharing

    Reply
  6. Alexandrina

    August 21, 2017 at 1:45 pm

    My God how hot a single recipe, I love, I will share with my friends who love to cook just like me.

    Reply
  7. Lazaro S.

    August 22, 2017 at 9:08 am

    Many thanks for sharing this delicious Mexican meatloaf recipe, I made it along with my wife and it was a real delight.

    Reply
    • Kathryn

      August 23, 2017 at 8:51 pm

      I'm so happy to hear you enjoyed it Lazaro!

      Reply
  8. App para fazer convites

    August 22, 2017 at 11:12 am

    Sunday, mainly. Sacred day of being able to wake up late and enjoy the family. The question always remains: What are we going to eat today?

    Reply
  9. Paul Lonet

    August 26, 2017 at 9:10 pm

    Great job. Thanks fos sharing.

    Reply
  10. Andressa Silva

    September 18, 2017 at 2:27 pm

    This recipe seems to be delicious, I'll try to make it here at home. I hope everyone likes it.

    Reply
    • Kathryn

      September 19, 2017 at 9:14 am

      I hope you enjoy it Andressa!

      Reply
  11. Gessica

    September 25, 2017 at 9:53 pm

    Muito bom este site

    Reply
  12. Tiago S.

    October 04, 2017 at 4:02 pm

    Mexican food is one of the tastiest in the world. It also has an incredible variety.

    Reply
  13. Anitta Torres

    November 09, 2017 at 7:14 am

    I loved this recipe. I'll do it today!

    Reply
    • Kathryn

      November 09, 2017 at 2:52 pm

      Thanks! I hope you enjoy it!

      Reply
  14. Vania

    January 29, 2018 at 8:42 am

    I feel like experiencing Mexican food. It must be very tasty.

    Reply
  15. joao vieira

    February 24, 2018 at 9:37 am

    My favorite =D

    Reply
  16. Julia

    March 14, 2018 at 11:52 am

    Delicious!! I'll try it, do it for my family!

    Reply
  17. Aline

    March 14, 2018 at 11:53 am

    I love Mexican food! I need to learn how to make these wonderful dishes !!!

    Reply
    • Kathryn

      March 14, 2018 at 8:02 pm

      This is a really easy one - hope you give it a try!

      Reply
  18. Jersey Girl Cooks

    March 21, 2018 at 4:25 pm

    Meatloaf is such comfort food. This looks great!

    Reply
    • Kathryn

      March 22, 2018 at 6:57 am

      Thanks! 😊

      Reply
  19. Megan

    March 21, 2018 at 6:32 pm

    Love the use of salsa in this meatloaf! And that it can all be mixed in one bowl and done!

    Reply
    • Kathryn

      March 22, 2018 at 6:55 am

      Thanks! It's so easy and so flavorful!

      Reply
  20. Shinee

    March 21, 2018 at 11:57 pm

    I love Mexican twist on classic meatloaf! YUM!

    Reply
    • Kathryn

      March 22, 2018 at 6:56 am

      Thanks Shinee!

      Reply
  21. Lauren Taylor

    March 22, 2018 at 11:59 pm

    This is the perfect twist for Taco Tuesday

    Reply
    • Kathryn

      March 23, 2018 at 4:36 pm

      Thanks! Keeps dinner fun for sure!

      Reply
  22. Megan @ MegUnprocessed

    March 23, 2018 at 6:30 pm

    I always like a one bowl recipe so there's not a lot of clean-up!

    Reply
    • Kathryn

      March 25, 2018 at 5:24 pm

      Yes! Isn't that so nice?!

      Reply
  23. Richa Gupta

    March 23, 2018 at 10:21 pm

    Wow love this amazing meatloaf recipe, looks yum!

    Reply
    • Kathryn

      March 25, 2018 at 5:24 pm

      Thanks so much!

      Reply
  24. Rachel

    April 02, 2018 at 8:01 pm

    I love Mexican food!

    Reply
  25. Sabrina Freitas

    June 12, 2018 at 2:55 pm

    Delicious! I'm going to do it tonight and surprise the whole family. Loved it!

    Reply
    • Kathryn

      June 12, 2018 at 8:14 pm

      Oh I'm so happy to hear that! I hope everyone enjoys it! 😊

      Reply
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Meet Kathryn

Hi there! I’m Kathryn Doherty, a cookbook author, mom of two, and devoted food and home cooking nut. I’ve got lots of easy recipes to help you get delicious food on the table for your family!

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